Endotoxins are protein toxins produced by bacteria and some parasites. They are a group of molecules that include lipopolysaccharides (LPS), lipoteichoic acid (LTA), peptidoglycans, and others. Endotoxin binds to and stimulates the release of cytokines, histamine, and prostaglandins. Endotoxin test is done through a lysate of the sample, e.g., blood, that is inactivated with formalin and assayed for bacterial endotoxin activity.
Microbiology Test
Microbiology tests are applicable in most laboratory facilities which include: sample collection, transportation, storage, and testing. These tests are used in the detection of bacteria and also for the identification of specific bacteria and other microorganisms. Furthermore, a part of the laboratory process of preparing and processing samples for research, diagnosis, and other laboratory procedures.
Molecular biology lab services
Molecular lab services are available for the following industries: pharmaceuticals, cosmetics, food, water, and medicine. These services are provided for the process development quality control of our client's products. These services help reduce the costs involved in product development and improve the safety of our clients' products. Molecular services are also helpful for improving product stability and quality, including DNA isolation, DNA sequencing, PCR and SNP analysis. The key features of molecular lab services are expertise, experience, high-quality standards, and cost-effectiveness.
Endotoxin Test
Endotoxin test has been used to detect the presence of bacteria in a sample, which is one of the applications of this test. Bacterial endotoxin test (BET) or bacterial endotoxins test is generally used to detect and measure pathogenic bacteria in blood products, cell cultures, pharmaceuticals, cosmetics, and vaccines. In the blood, bacteria produce endotoxins that activate the body's immune system, the reason why cells require a specific level of endotoxin to stay alive. These endotoxins can be released during infection and inflammation, leading to bacterial resistance to antibiotics. There are two types of bacterial endotoxin test methods performed for the same purpose: qualitative (BET-Q) and quantitative (BET-QA).
Conclusion
To sum up, endotoxin test is needed in many laboratory facilities. It is used to detect and measure the number of bacterial endotoxins present in samples and ensure samples' safety and personnel.